A proposed sustainability index for synthesis plans based on input provenance and output fate: application to academic and industrial synthesis plans for vanillin as a case study

• John Andraos

Beilstein J. Org. Chem. 2020, 16, 2346–2362, doi:10.3762/bjoc.16.196

• ) consumption, input enthalpic energy (IEE) consumption, Rowan solvent greenness index (RSGI), and sustainability index (SI). Keywords: Borda count; green chemistry; input enthalpic energy; process mass intensity; poset dominance analysis; Rowan solvent greenness index; sacrificial reagent; sustainability

• under consideration is large. Table 5 summarizes the main results of the poset dominance analysis for all vanillin plans considered. We observe that plans p7 (Givaudan–Roure), p8 (Haarmann and Reimer), and p18 (percolation extraction whole vanilla beans) have the highest number of pairwise dominances of

• vanillin. Summary of computed values for five attributes for 22 synthesis plans of vanillin. Summary of Borda count results for 22 synthesis plans of vanillin.a Summary of pairwise poset dominance analysis for 22 synthesis plans of vanillin based on 5 attribute categories.a Summary of Borda count and poset